Today I finished validating a CpG O/E workflow Steven put together by analyzing the C. gigas transcriptome and comparing it to the results of Gavery and Roberts (2010). The results agreed well. Notably, there was a similar bimodal distribution of CpG O/E, and major gene categories showed similar levels of CpG O/E (e.g., cell adhesion around 0.7 and DNA metabolism around 0.5).
[iframe src=”http://nbviewer.ipython.org/url/eagle.fish.washington.edu/astrangia/nb/CpG_ratio_graph.ipynb” width=”100%” same_height_as=”window” scrolling=”yes”]