Lab Introduction
Dr. Rose employs several approaches to gain insight into how neurons are uniquely adapted to modify themselves following a change in stimulus input. Research in the Rose lab utilizes the microscopic C. elegans model system to investigate processes at the single-neuron level within an intact animal model. Dr. Rose also employs dissociated hippocampal neuron cultures to observe protein redistribution and aggregation following induced activity. Taken together, these two research directions converge to reveal how alterations in ongoing signaling change neurons and how these changes can be reflected in the whole, behaving animal.
