I like the idea of using light as a way of manipulation of that way someone looks, such as the strategies that cinematographers used with people in movies. I find it interesting that using light on a subject can greatly change the character to a viewer, and change the tone in the room. Wherever the shadows fall on a face of a subject could attract or frighten a viewer.
I have very limited experience with natural and artificial lighting, but I can say one is not easier to photograph with than the other. I like using artificial light because I can control more what I am doing, but it is still difficult to find what I am looking for in a studio environment. Natural lighting is not consistent or planned, but can be perfect at the right times. Also it is a nice way to experiment and understand what the best times of day are for photos. Harsh daylight is not always ideal, but cloudy days usually are more successful.